Medical Definition of CD4/CD8 count

1. The ratio of the number of helper-inducer T lymphocytes to cytotoxic-suppressor T lymphocytes, as measured by monoclonal antibodies to the CD4 surface antigen found on helper-inducer T-cells, and the CD8 surface antigen found on cytotoxic-suppressor T-cells. In healthy individuals, the H/S ratio ranges between 1.6 and 2.2.When the body mounts an immune response, as against a virus or a transplant, the ratio is almost always reduced because of a decrease in the number of circulating helper-inducer cells and an increase in suppressor cells. The CD4/CD8 count has been used to monitor for signs of organ rejection after transplants, and more recently has become a tool for assessing the relative condition of HIV patients. With the CD4 absolute count and the CD4 lymphocyte percentage, it provides a way of gauging the progression from HIV to AIDS. (05 Mar 2000)

Lexicographical Neighbors of CD4/CD8 Count

CD18
CD19
CD2
CD20
CD26
CD27
CD28
CD29
CD3
CD30
CD31
CD34
CD36
CD4
CD4-positive T-lymphocytes
CD4/CD8 count (current term)
CD40
CD44
CD45
CD45 phosphatase
CD4:CD8 ratio
CD4 T cell
CD4 cell
CD4 cell count
CD4 immunoadhesins
CD4 lymphocyte
CD4 lymphocyte count
CD5
CD50
CD55

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