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Medical Definition of F thalassaemia
1. Thalassaemia due to a gene that depresses synthesis of both beta-and d-globin chains by the chromosome bearing the abnormal gene. Heterozygous state: thalassaemia minor with Hb F comprising 5 to 30% of total haemoglobin but distributed unevenly among cells, Hb A2 reduced or normal. Homozygous state: moderate anaemia with only Hb F present, no Hb A or Hb A2. Synonym: F thalassaemia. (05 Mar 2000)