Medical Definition of IgM nephropathy
1.
Inflammation of the kidney glomerulus (blood filtering portion of the kidney) due to the abnormal deposition of IgM antibody in the mesangium layer of the glomerular capillary. A form of glomerulonephritis that appears to be caused by an abnormal immune response. This disorder generally manifests as nephrotic syndrome.
Symptoms include swelling, dark urine, weight gain, hypertension, anorexia and bloody urine.
Acronym: MPGN
(05 Jan 1998)
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