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Medical Definition of Lawrence-Seip syndrome
1. Loss of subcutaneous fat, which may be total, congenital, and associated with hepatomegaly, excessive bone growth, and insulin-resistant diabetes. Synonym: Lawrence-Seip syndrome, lipoatrophia, lipoatrophic diabetes. Origin: G. Lipos, fat, + a-, priv. + trophe, nourishment (05 Mar 2000)