Definition of Lesch-Nyhan syndrome

1. Noun. A rare inherited genetic disorder, caused by a deficiency of HGPRT, in which uric acid builds up in all body fluids. ¹

¹ Source: wiktionary.com

Medical Definition of Lesch-Nyhan syndrome

1. A sex-linked recessive inherited disease in humans that results from mutation in the gene for the purine salvage enzyme hypoxanthine phosphoribosyltransferase (HGPRT), located on the X chromosome. Results in severe mental retardation. It is characterised by physical and mental retardation, and distressing behavioural abnormalities, such as compulsive self mutilation, hyperuricaemia, and choreoathetosis, and renal failure. Excess uric acid production exists due to the absence of an enzyme essential to purine metabolism. Inheritance: sex-linked recessive. (22 Sep 2002)

Lesch-Nyhan Syndrome Pictures

Click the following link to bring up a new window with an automated collection of images related to the term: Lesch-Nyhan Syndrome Images

Lexicographical Neighbors of Lesch-Nyhan Syndrome

Lermoyez
Lermoyez' syndrome
Lerner
Lerner homeostasis
Leroi
Leroy
Leroy Robert Paige
Lerwick
Lesath
Lesbonian
Lesbos
Lesbœufs
Lescol
Leser-Trelat sign
Lesley
Leslie
Leslie Howard
Leslie Howard Stainer
Leslie Richard Groves
Leslie Townes Hope
Lesotho
Lesotho monetary unit
Lespedeza bicolor
Lespedeza cuneata
Lespedeza sericea
Lespedeza stipulacea

Other Resources Relating to: Lesch-Nyhan syndrome

Search for Lesch-Nyhan syndrome on Dictionary.com!Search for Lesch-Nyhan syndrome on Thesaurus.com!Search for Lesch-Nyhan syndrome on Google!Search for Lesch-Nyhan syndrome on Wikipedia!

Search