Medical Definition of Machado-Joseph

1. A rare form of hereditary ataxia, characterised by onset in early adult life of progressive, spinocerebellar and extrapyramidal disease with external ophthalmoplegia, rigidity dystonia symptoms, and, often, peripheral amyotrophy; found predominantly in people of Azorean ancestry; autosomal dominant inheritance. Synonym: Azorean disease, Portuguese-Azorean disease. Origin: Surnames of two families studied in major descriptions of the disease. (05 Mar 2000)



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Lexicographical Neighbors of Machado-Joseph

MaceiĆ³
Macerata
Macewen's sign
Macewen's symptom
Macewen's triangle
Macgillycuddy's Reeks
Mach
Mach's band
Mach's principle
Mach Zehnder system
Mach effect
Mach line
Mach number
Macha
Machado-Guerreiro test
Machado-Joseph (current term)
Machaeranthera
Machaeranthera bigelovii
Machaeranthera tanacetifolia
Machaeranthera tortifoloia
Machame
Machead
Macheads
Machen
Machiavel
Machiavelli
Machiavellian
Machiavellianism
Machiavellians
Machiavellis

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