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Definition of Polycomb
1. Noun. (biochemistry) A protein (or one of a larger group) whose function is to modify gene expression via changes to chromatin ¹
¹ Source: wiktionary.com
Medical Definition of Polycomb
1. Drosophila gene, which when mutated leads to extra sex combs on the legs of male flies, suggesting that the posterior legs have become anterior legs. There are at least 10 genes in the Polycomb group, they are thought to act by transcriptional silencing of homeotic genes. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)