Definition of Acromegaly

1. Noun. Enlargement of bones of hands and feet and face; often accompanied by headache and muscle pain and emotional disturbances; caused by overproduction of growth hormone by the anterior pituitary gland (due to a tumor).

Exact synonyms: Acromegalia
Terms within: Hyperpituitarism
Generic synonyms: Hypertrophy
Derivative terms: Acromegalic

Definition of Acromegaly

1. n. Chronic enlargement of the extremities and face.

Definition of Acromegaly

1. Noun. (disease) A chronic disease marked by enlargement of the bones of the extremities, face, and jaw that is caused by over-activity of the pituitary gland. ¹

¹ Source:

Definition of Acromegaly

1. [n -LIES]

Medical Definition of Acromegaly

1. A condition that results from the excess production of growth hormone in the anterior lobe of the pituitary gland. Acromegaly is characterised by enlarged facial features, enlarged jaw, enlarged frontal bone of skull, widely spaced teeth and enlargement of the bones of the extremities. Other features include enlargement of the lips and nose, thickening of the soft tissues of the face, somnolence, moodiness and decreased libido. (13 Nov 1997)

Acromegaly Pictures

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Lexicographical Neighbors of Acromegaly

acroleic acids
acromegalic gigantism
acromegaly (current term)
acromelic dwarfism
acromial angle
acromial arterial network
acromial artery
acromial articular facies of clavicle
acromial articular surface of clavicle
acromial branch of suprascapular artery
acromial branch of thoracoacromial artery

Literary usage of Acromegaly

Below you will find example usage of this term as found in modern and/or classical literature:

1. The American Journal of the Medical Sciences by Southern Society for Clinical Investigation (U.S.) (1919)
"acromegaly: round-cell sarcoma of pituitary gland. ... Admitted January 10, 1919; Clinical No. 5808. Summary. acromegaly ..."

2. Monographic Medicine by William Robie Patten Emerson, Guido Guerrini, William Brown, Wendell Christopher Phillips, John Whitridge Williams, John Appleton Swett, Hans Günther, Mario Mariotti, Hugh Grant Rowell (1916)
"(g) Differential Diagnosis of acromegaly acromegaly affects both the head and the extremities, and n?ay he confused (1) with diseases that affect all these, ..."

3. The Ductless Glandular Diseases by Wilhelm Falta (1916)
"The opposition of the clinical pictures of acromegaly and hypophysial dystrophy. 2. ... Early acromegaly.—The statements thus far set forth as to the ..."

4. A Text-book of Pathology by William George MacCallum, Harry Gideon Wells (1907)
"... stand the following facts : acromegaly AND THE HYPOPHYSIS Although in nearly all cases of acromegaly alterations are observed in the hypophysis, ..."

5. The Practitioner by Gale Group, ProQuest Information and Learning Company (1891)
"In the acromegaly of Marie, which is a disease of constant type, ... acromegaly following Fright.—A case of acromegaly in which shock from a fright appeared ..."

6. Journal of Nervous and Mental Disease by Philadelphia Neurological Society, American Neurological Association, Chicago Neurological Society, New York Neurological Association (1899)
"REPORT OF A CASE OF TUMOR OF THE HYPOPHYSIS WITHOUT acromegaly. ... We believe, for reasons which will appear later, that acromegaly is due to the disease ..."

7. Diseases of the nervous system: A Text-book of Neurology and Psychiatry by Smith Ely Jelliffe, William Alanson White (1917)
"Absolute loss of the pituitary occurs very rarely. FIG. 98.—acromegaly. ... acromegaly is characterized by the gradual enlargement of the bones of the nose, ..."

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