Definition of Actinomycin

1. Noun. Any of various red antibiotics isolated from soil bacteria.

Generic synonyms: Antibiotic, Antibiotic Drug



Definition of Actinomycin

1. Noun. (protein pharmaceutical drug) Any of a class of toxic polypeptide antibiotics found in soil bacteria of genus ''Streptomyces''. ¹

¹ Source: wiktionary.com

Definition of Actinomycin

1. [n -S]

Medical Definition of Actinomycin

1. A group of peptide antibiotic agents, isolated from several species of Streptomyces (originally Actinomyces), that are active against Gram-positive bacteria, fungi, and neoplasms. Actinomycins are chromopeptides, most containing the chromophore actinocin, and are derivatives of phenoxazine that differ in their amino acids and their sequence in the peptide chains; they form complexes with DNA and therefore inhibit RNA synthesis, primarily the ribosomal type. Actinomycin A, the first of the actinomycin's isolated in crystalline form. (05 Mar 2000)

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Lexicographical Neighbors of Actinomycin

actinometry
actinomorphic
actinomorphies
actinomorphous
actinomorphy
actinomycelial
actinomyces
actinomyces viscosus
actinomycetaceae
actinomycetal
actinomycetales
actinomycetales infections
actinomycete
actinomycetes
actinomycetous
actinomycin (current term)
actinomycin C
actinomycin D
actinomycin F1
actinomycin lactonase
actinomycins
actinomycoma
actinomycoses
actinomycosis
actinomycotic
actinomycotic appendicitis
actinomyxidian
actinon
actinoneuritis
actinons

Literary usage of Actinomycin

Below you will find example usage of this term as found in modern and/or classical literature:

1. Science by American Association for the Advancement of Science (1883)
"Groups (12 tubes) of normal serum, normal serum plus actinomycin D, and active serum without actinomycin D were treated similarly. The contents of all tubes ..."

2. Oxygen/Nitrogen Radicals and Cellular Injury edited by Kenneth B. Adler, Robert D. Devlin, Val Vallyathan (2000)
"The mRNA half-life in MDCK cells was measured using actinomycin D to prevent new RNA synthesis; the remaining Na,K- ATPase mRNA was quantitated using ..."

3. Proceedings of the Society for Experimental Biology and Medicine (1903)
"This period is remarkably similar to that obtained by Pool and Lipner (1,2) after intrafollicular injection of actinomycin D, cycloheximide, ..."

4. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"The pharmacological PA stimulation required both RNA and protein syntheses, as evidenced by inhibition by actinomycin D and cycloheximide. ..."

5. Impacts Of Antibiotic-resistant Bacteria by DIANE Publishing Company (1996)
"... permeability barrier to the entry of the antibiotic actinomycin D. While BPI was bactericidal to several strains of E. coli and Salmonella typhimurium, ..."

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