Definition of Aphidicolin

1. Noun. A tetracyclic diterpene antibiotic with antiviral and antimitotical properties. ¹



¹ Source: wiktionary.com

Medical Definition of Aphidicolin

1. Tetradecahydro-3,9-dihydroxy-4,11b-dimethyl-8,11a-methano-11ah-cyclohepta(a)naphthalene-4,9-dimethanol. An antiviral antibiotic produced by cephalosporium aphidicola and other fungi. It inhibits the growth of eukaryotic cells and certain animal viruses by selectively inhibiting the cellular replication of DNA polymerase II or the viral-induced DNA polymerases. The drug may be useful for controlling excessive cell proliferation in patients with cancer, psoriasis or other dermatitis with little or no adverse effect upon non-multiplying cells. Pharmacological action: antiviral agents, enzyme inhibitors. Chemical name: 9,15-Cyclo-C,18-dinor-14,15-secoandrostane-4,17-dimethanol, 3,17-dihydroxy-4-methyl-, (3alpha,4alpha,5alpha,17alpha)- (12 Dec 1998)

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Lexicographical Neighbors of Aphidicolin

aphetism
aphetisms
aphetize
aphetized
aphetizes
aphetizing
aphicide
aphicides
aphid
aphid lion
aphides
aphidian
aphidians
aphidicide
aphidicides
aphidicolin (current term)
aphidivorous
aphidlike
aphidophagous
aphids
aphilanthropy
aphilopony
aphilosophical
aphis lion
aphlogistic
aphobia
apholate
apholates
aphonia

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