Medical Definition of Arachidonate 12-lipoxygenase
1.
An enzyme that catalyses the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-hpete) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-hete). The 12-hydroperoxides are preferentially formed in platelets.
Chemical name: Arachidonate:oxygen 12-oxidoreductase
Registry number: EC 1.13.11.31
(12 Dec 1998)
Lexicographical Neighbors of Arachidonate 12-lipoxygenase
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