Medical Definition of Bcl-2

1. Two variants of this oncogene are recognised. 1. Bcl-2: A proto-oncogene, activated by chromosome translocation in human B-cell lymphomas (hence bcl). Encodes a plasma membrane protein. The gene product inhibits programmed cell death (apoptosis) and is homologous with the worm gene ced 9. See: ced mutant. 2. Bcl-3: An oncogene associated with some cases of B-cell chronic lymphocytic leukaemias. The protein product contains seven ankyrin repeats very similar to those found in I kappa B. Seems to interfere with binding of 50 kD subunit of NF kappa B to DNA. (24 Mar 1998)



Bcl-2 Pictures

Click the following link to bring up a new window with an automated collection of images related to the term: Bcl-2 Images

Lexicographical Neighbors of Bcl-2

bazooms
bazoos
bazouki
bazoukis
bazuco
bazuko
bazzite
bazzites
bbiab
bbiaf
bbiafm
bbl
bbls
bbs
bcl
bcl-2 (current term)
bcl-3
bday
bdays
bdellatomy
bdellin
bdellium
bdelliums
bdelloid
bdelloid rotifer
bdelloid rotifers
bdelloidea
bdelloids
bdellometer
bdellomorpha

Other Resources Relating to: Bcl-2

Search for Bcl-2 on Dictionary.com!Search for Bcl-2 on Thesaurus.com!Search for Bcl-2 on Google!Search for Bcl-2 on Wikipedia!

Search