Medical Definition of Chloramphenicol o-acetyltransferase

1. An enzyme that catalyses the acetylation of chloramphenicol to yield chloramphenicol 3-acetate. Since chloramphenicol 3-acetate does not bind to bacterial ribosomes and is not an inhibitor of peptidyltransferase, the enzyme is responsible for the naturally occurring chloramphenicol resistance in bacteria. The enzyme, for which variants are known, is found in both gram-negative and gram-positive bacteria. Chemical name: Acetyl-CoA-chloramphenicol 3-O-acetyltransferase Registry number: EC 2.3.1.28 (12 Dec 1998)



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Lexicographical Neighbors of Chloramphenicol O-acetyltransferase

chloramides
chloramine
chloramine-T
chloramine B
chloramine T
chloramines
chloraminophene
chloramiphene
chloramizole
chloramphenicol
chloramphenicol 3'-O-phosphotransferase
chloramphenicol acetyltransferase
chloramphenicol acetyltransferase gene
chloramphenicol amidase
chloramphenicol o-acetyltransferase (current term)
chloramphenicol palmitate
chloramphenicol resistance
chloramphenicol sodium succinate
chlorane
chloranil
chloranilic acid
chlorapatite
chlorapatites
chlorargyrite
chlorartinite
chlorate
chlorates
chloratian
chloraurate

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