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Medical Definition of Coated vesicles
1. Vesicles formed when cell-membrane coated pits (coated pits, cell-membrane) invaginate and pinch off. The outer surface of these vesicles is covered with a lattice-like network of the protein clathrin. Shortly after formation, however, the clathrin coat is removed and the vesicles are referred to as endosomes. (12 Dec 1998)