Definition of Coloboma

1. n. A defect or malformation; esp., a fissure of the iris supposed to be a persistent embryonic cleft.

Definition of Coloboma

1. Noun. An abnormal hole present from birth in one of the structures of the eye, such as the lens, eyelid, or retina. ¹

¹ Source:

Definition of Coloboma

1. a lesion of the eye [n -MATA]

Medical Definition of Coloboma

1. Congenital anomaly in which some of the structures of the eye are absent due to incomplete fusion of the foetal intraocular fissure during gestation. (12 Dec 1998)

Coloboma Pictures

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Lexicographical Neighbors of Coloboma

coloboma lentis
colobus monkey

Literary usage of Coloboma

Below you will find example usage of this term as found in modern and/or classical literature:

1. Text-book of Ophthalmology by Ernst Fuchs (1911)
"Congenital coloboma of the iris is always situated below. ... The sphincter encompasses the pupil and the coloboma, too, as far as Flo. 198. Fir.. 199 FIG. ..."

2. Diagnostics of the Fundus Oculi by Edward Leroy Oatman (1920)
"Natal hemorrhages or ruptures of the choroid may result in cicatrices that cannot, with certainty, be differentiated from congenital coloboma. ..."

3. A Treatise on the Diseases of the Eye by John Soelberg Wells (1883)
"coloboma OF THE CHOROID. boma of the choroid exists without there being any cleft in the iris. I had lately under my care at Moorfields, a patient in whose ..."

4. Molecular Neurobiology: Proceedings of the Second Nimh Conference by Steven Zalcman (1995)
"As one approach to assess SNAP-25 function, we identified a mouse mutation coloboma located on chromosome 2 that comprises a deletion of the entire Snap ..."

5. Annals of Ophthalmology (1917)
"Fuchs' coloboma of the optic nerve or the conus below, that condition we so frequently see in our patients, and that has, to some extent, become linked in ..."

6. Modern ophthalmology: A Practical Treatise on the Anatomy, Physiology, and by James Moores Ball (1908)
"coloboma of the Iris may exist alone, but generally is found with a like condition ... In most cases the coloboma Fig. 256 —Congenital coloboma of the iris. ..."

7. Diseases of the Eye: A Practical Treatise for Students of Ophthalmology by George Andreas Berry (1893)
"The true coloboma of the choroid is always met with down- - FIG. 91.—coloboma of the choroid (inverted image). wards, or downwards and inwards, ..."

8. The American Journal of the Medical Sciences by Southern Society for Clinical Investigation (U.S.) (1859)
"IV., for July, 1858). that so many cases of coloboma iridis have come under his observation, that he believes it to be a very common congenital defect, ..."

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