Medical Definition of Cos cell
1.
A cell line derived from the african green monkey and used for transfection and cloning. The cells are simian fibroblasts (CV 1 cells) transformed by SV40 that is deficient in the origin of replication region.
They express large T antigen constitutively and if transfected with a vector containing a normal SV40 origin have all the other early viral genes necessary to generate multiple copies of the vector and thus to give very high levels of expression.
(04 Jul 1999)
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Lexicographical Neighbors of Cos Cell
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