Medical Definition of Dideoxynucleosides
1.
Nucleosides that have two hydroxy groups removed from the sugar moiety. The majority of these compounds have broad-spectrum antiretroviral activity due to their action as antimetabolites. The nucleosides are phosphorylated intracellularly to their 5'-triphosphates and act as chain-terminating inhibitors of viral reverse transcription.
Pharmacological action: antimetabolites, antiviral agents, reverse transcriptase inhibitors.
(12 Dec 1998)
Lexicographical Neighbors of Dideoxynucleosides
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