Definition of Dopamine
1. Noun. A monoamine neurotransmitter found in the brain and essential for the normal functioning of the central nervous system; as a drug (trade names Dopastat and Intropin) it is used to treat shock and hypotension.
Definition of Dopamine
1. Noun. (neurotransmitter) A neurotransmitter associated with movement, attention, learning, and the brain’s pleasure and reward system. ¹
¹ Source: wiktionary.com
Definition of Dopamine
1. a form of dopa used to stimulate the heart [n -S]
Medical Definition of Dopamine
1.
A catecholamine neurotransmitter and hormone (153 D), formed by decarboxylation of dehydroxyphenylalanine (dopa). A precursor of adrenaline and noradrenaline.
Pharmacologic action: 1. Precursor of norepinephrine 2. Stimulates dopaminergic, alpha and beta-1 adrenergic receptors: 3. Dopaminergic (1-2 mcg/kg per min): cerebral, renal, and mesenteric vasodilation increase urine output 4. Mixed alpha and beta-1 (2-10 mcg/kg per min): increases cardiac ouput with moderate increase systemic vascular resistance 5. Predominantly alpha (>20 mcg/kg per min): increases systemic vascular resistance
Uses: 1. Treat hypotension associated with bradycardia 2. Stimulate cardiac output and urine output
Dose: 1. Start infusion at 1-5 mcg/kg per min and titrate to effect. 2. Use the lowest dose that provides the desired hemodynamic improvement. 3. Do not exceed 20 mcg/kg per min.
Potential complications: 1. May increase pulmonary pressure and worsen pulmonary congestion. 2. May increase myocardial work without improving coronary blood flow, exacerbating myocardial ischemia 3. Stimulates heart rate and may cause supraventricular or ventricular arrhythmias
(15 Mar 2000)
Lexicographical Neighbors of Dopamine
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