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Medical Definition of Dual recognition hypothesis
1. An outmoded hypothesis that is known to be incorrect now that the structure of the T-cell receptor is known. The proposal was that viral (and some chemical) antigens were recognised in association with histocompatibility antigens by separate receptors on the T-cell. The generation of cytotoxic T-cells was by association with Class I MHC antigens, of T helper cells by association with Class II MHC antigens. See: altered self hypothesis. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Dual Recognition Hypothesis
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