Definition of Dystroglycan

1. Noun. (protein) A glycoprotein associated with dystrophin ¹

¹ Source: wiktionary.com

Medical Definition of Dystroglycan

1. Complex composed of two proteins and dystroglycans (formerly known as 156DAG and 43DAG / A3a respectively) derived from a single precursor by proteolytic cleavage. Dystroglycan is a transmembrane protein that associates with dystrophin in the cytoplasm and dystroglycan, an extracellular glycoprotein, on the exterior face. Dystroglycan binds to merosin, thus linking actin through dystrophin and dystroglycan to the extracellular matrix. Also associates with sarcoglycan. Dystrophin deficiency leads to a deficiency in the appearance of these proteins on the sarcolemma, even though they are not themselves defective. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

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Lexicographical Neighbors of Dystroglycan

dystome
dystonia
dystonia lenticularis
dystonia musculorum deformans
dystonias
dystonic
dystonic reaction
dystonic torticollis
dystopia
dystopian
dystopias
dystopic
dystopically
dystrobrevin
dystrobrevins
dystroglycan (current term)
dystrophia
dystrophia adiposogenitalis
dystrophia brevicollis
dystrophia myotonica
dystrophia unguium
dystrophia ungulae
dystrophias
dystrophic
dystrophic calcification
dystrophic calcinosis
dystrophies
dystrophin
dystrophinopathies
dystrophinopathy

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