Definition of Factor xii

1. Noun. Coagulation factor whose deficiency results in prolongation of clotting time of venous blood.

Exact synonyms: Hageman Factor
Generic synonyms: Clotting Factor, Coagulation Factor

Medical Definition of Factor xii

1. Stable blood coagulation factor activated by contact with the subendothelial surface of an injured vessel. Along with prekallikrein, it serves as the contact factor that initiates the intrinsic pathway of blood coagulation. Kallikrein activates factor xii to xiia. Deficiency of factor xii, also called the hageman trait, leads to increased incidence of thromboembolic disease. Chemical name: Blood-coagulation factor XII (12 Dec 1998)

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Lexicographical Neighbors of Factor Xii

factor vii
factor vii assay
factor vii deficiency
factor viia
factor viii
factor viii assay
factor viii deficiency
factor viiia
factor x
factor x assay
factor x deficiency
factor xa
factor xi
factor xi deficiency
factor xia
factor xii (current term)
factor xii assay
factor xii deficiency
factor xiia
factor xiii
factor xiii deficiency
factorial experiment

Literary usage of Factor xii

Below you will find example usage of this term as found in modern and/or classical literature:

1. A System of the Shipping and Navigation Laws of Great Britain: And of the by Francis Ludlow Holt (1824)
"... exist where the principal would be bound by the pledge of hia factor. XII. We have deemed it necessary to cite the above cases, chiefly with the view of ..."

2. Health Consequences of Smoking: Cardiovascular Disease: Report of the by C. Everett Koop, M.D., DIANE Publishing Company (2004)
"(10) BECKER, GG, DUBIN, T. Activation of factor XII by tobacco glycoprotein. Journal of Experimental Medicine 146(2): 457^467, August 1,1977. ..."

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