Definition of Farnesylation
1. Noun. The act or process of farnesylating. ¹
¹ Source: wiktionary.com
Medical Definition of Farnesylation
The farnesyl group is the linear grouping of three isoprene units.
It is specifically attached to proteins that contain the C terminal motif CAAX by cleavage and addition to the SH group of C, the free carboxylate group is also methylated. Believed to act as a membrane attachment device.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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