Medical Definition of Fish-odour syndrome

1. An inborn error of metabolism associated with an offensive body odour, the smell of rotting fish, due to the excessive excretion of trimethylaminuria (TMA) in urine, sweat, and breath. Persons with TMA may experience tachycardia (fast heart rate) and severe hypertension (high blood pressure) after eating cheese (which contains tyramine) and after using nasal sprays containing epinephrine. TMA is caused by a mutation (change) in the gene for an enzyme, flavin-containing monooxygenase-3 (FMO3) encoded by a gene on chromosome 1. The FMO3 enzyme metabolises tyramine (which is in cheese). The syndrome is associated with various psychosocial reactions, including social isolation, clinical depression and attempted suicide. (12 Dec 1998)



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Lexicographical Neighbors of Fish-odour Syndrome

fiscs
fisetic
fisetin
fisgig
fisgigs
fish
fish-bellied
fish-block
fish-eating grin
fish-eye lens
fish-finger
fish-fly
fish-knife
fish-mouth meatus
fish-mouth mitral stenosis
fish-odour syndrome (current term)
fish-out-of-water
fish-pond
fish-tackle
fish-tail
fish-trap
fish-worship
fish 'n' chips
fish and chips
fish ball
fish berry
fish bowl
fish bowl granuloma
fish bowls
fish cake

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