Medical Definition of Formyl peptide

1. Informal term for small peptides with a formylated N terminal methionine and usually a hydrophobic amino acid at the carboxy terminal end (fMetLeuPhe is the most commonly used). These peptides stimulate the motor and secretory activities of leucocytes, particularly neutrophils and monocytes, that have a specific receptor (about 60 kD) of high affinity (Kd approximately 10exp 8M). Leucocytes show chemotaxis towards formyl peptides but the term chemotactic peptides understates the range of activities the molecules will trigger. Thought to be synthetic analogues of bacterial signal sequences though this is unproven. The leucocytes of many animals (e.g. Pig, cow, chicken) do not respond. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)



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Lexicographical Neighbors of Formyl Peptide

formulization
formulizations
formulize
formulized
formulizes
formulizing
formulæ
formwork
formworks
formycin B
formycins
formyl
formyl-coenzyme A transferase
formyl-methenyl-methylenetetrahydrofolate synthetase
formyl methionine
formyl peptide (current term)
formyl sterol oxidase
formylase
formylate
formylated
formylation
formylations
formylglutamate amidohydrolase
formylmethanofuran-tetrahydromethanopterin formyltransferase
formylmethanofuran dehydrogenase
formylmethionine
formylmethionyl-tRNA
formyls
formyltetrahydrofolate deformylase
formyltetrahydrofolates

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