Lexic.us

¹ Source: wiktionary.com

Definition of Genistein

1. [n -S]

Medical Definition of Genistein

1. An isoflavonoid derived from soy products. It inhibits protein-tyrosine kinase and topoisomerase-II (DNA topoisomerase (ATP-hydrolysing)) activity and is used as an antineoplastic and antitumour agent. Experimentally, it has been shown to induce g2 phase arrest in human and murine cell lines. Pharmacological action: anticarcinogenic agents, antineoplastic agent, enzyme inhibitors, growth inhibitors, parasympatholytics. (12 Dec 1998)

Lexicographical Neighbors of Genistein

Literary usage of Genistein

Below you will find example usage of this term as found in modern and/or classical literature:

1. Alternative Medicine: Expanding Medical Horizons by DIANE Publishing Company (1995)
"Studies indicate a correlation between a high intake of foods containing genistein (soy products) and a low incidence of hormone-dependent cancers such as ..."

2. A Dictionary of Applied Chemistry by Thomas Edward Thorpe (1921)
"genistein crystallises in long colourless needles ; mp 291°-293° (Perkin and Horsfall, Chem. Soc. Trans. 1900, 77, 1312) ; soluble in alkalis with a pale ..."

3. A Dictionary of Applied Chemistry by Thomas Edward Thorpe (1912)
"It is purified by crystallisation from acetic acid, and by conversion into the acetyl derivative. genistein crystallises in long colourless needles : mp ..."

4. Oxygen/Nitrogen Radicals and Cellular Injury edited by Kenneth B. Adler, Robert D. Devlin, Val Vallyathan (2000)
"Effect of genistein on PLA2 and PLD activities and protein tyrosine ... Cells were washed in MEM and preincubated with 100 uM genistein for 60 min. ..."

5. The Natural Organic Colouring Matters by Arthur George Perkin, Arthur Ernest Everest (1918)
"genistein crystallises in long colourless needles ; melting-point 291 — 293° ... On digestion with boiling 50 per cent, potassium hydroxide, genistein gives ..."

6. Pigments of Flowering Plants by Nellie Antoinette Wakeman (1913)
"Of the pigments of known constitution only one, genistein, is believed to be ... genistein. While the constitution of genistein has not yet been fully ..."

7. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"For example, genistein has substantially greater ER binding capacity and estrogenic activity than daidzein. Interestingly, these two chemicals differ only ..."

Other Resources: