Medical Definition of Germ line transformation

1. Micro injection of foreign DNA into an early embryo, so that it becomes incorporated into the germ line of the individual and thus stably inherited in subsequent generations of transgenic organisms. Typically, the DNA would be a reporter gene or cDNA in a vector such as a transposon, that might also carry a visible marker gene such as eye or coat colour), so that successful transformation could readily be detected. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)



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Lexicographical Neighbors of Germ Line Transformation

gerlind
germ
germ-free animal
germ-free isolator
germ-free life
germ-line mutation
germ-plasm
germ cell tumour
germ cells
germ layer
germ layer theory
germ layers
germ line
germ line gene therapy
germ line transformation (current term)
germ nucleus
germ pore
germ theory
germ tube
germ tube test
germ warfare
germacrene
germain
germaine
germaines
germains
german
german measles

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