Definition of Granulation tissue

1. Noun. New connective tissue and tiny blood vessels that form on the surfaces of a wound during the healing process.

Exact synonyms: Granulation
Generic synonyms: Connective Tissue
Specialized synonyms: Proud Flesh
Derivative terms: Granulate

Medical Definition of Granulation tissue

1. Highly vascularised tissue that replaces the initial fibrin clot in a wound. Vascularisation is by ingrowth of capillary endothelium from the surrounding vasculature. The tissue is also rich in fibroblasts (that will eventually produce the fibrous tissue) and leucocytes. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Granulation Tissue Pictures

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Lexicographical Neighbors of Granulation Tissue

granulated opium
granulated sugar
granulation tissue (current term)
granulationes arachnoideales
granule cell
granule cell of connective tissue
granule cells

Literary usage of Granulation tissue

Below you will find example usage of this term as found in modern and/or classical literature:

1. The Journal of Infectious Diseases by Infectious Diseases Society of America, John Rockefeller McCormick Memorial Fund, John McCormick Institute for Infectious Diseases (1914)
"... together with experiments in which agar was used to cause the formation of nodules of granulation tissue. The human tubercle bacilli used in these ..."

2. Surgery, Gynecology & Obstetrics by The American College of Surgeons, Franklin H. Martin Memorial Foundation (1922)
"The lower cut end is firmly glued down to the granulation tissue, and it appears that ... This latter is granulation tissue presenting the earlier stages of ..."

3. An Introduction to pathology and morbid anatomy by Thomas Henry Green (1871)
"granulation tissue must thus be regarded as the most elementary form of ... They consist iu the first place of a granulation tissue ; this becomes very ..."

4. The Journal of Experimental Medicine by Rockefeller University, Rockefeller Institute, Rockefeller Institute for Medical Research (1907)
"The tissue was also examined by Dr. Bunting who made the following note: " The specimen consists of granulation tissue upon a basis of white fibrous tissue. ..."

5. General Surgical Pathology and Therapeutics, in Fifty Lectures by Theodor Billroth (1890)
"Fine sections cannot be made of granulation tissue, just taken from a wound; ... If you harden the granulation tissue in alcohol, color Ihe see lion with ..."

6. The Science and Art of Surgery: A Treatise on Surgical Injuries, Diseases by John Eric Erichsen, Marcus Beck (1885)
"The granulation-tissue replacing the cancellous bone may be absorbed apparently as the result of the pressure exerted upon it by the weight of tie trunk. ..."

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