Medical Definition of Hexosebisphosphatase
1.
This key intermediate in glycolysis and gluconeogenesis (a hexose diphosphate) was discovered by Arthur Harden and William Young in 1905.
In the third step of glycolysis, fructose 6-phosphate and ATP are converted to fructose 1,6-bisphosphate and ADP with the aid of phosphofructokinase. In step 4, fructose 1,6 bisphosphate (with the aid of aldolase) is cleaved into duhydroxyacetone phosphate and glyceraldehyde 3-phosphate.
Synonym: hexosebisphosphatase, hexosediphosphatase.
(08 Mar 2000)
Lexicographical Neighbors of Hexosebisphosphatase
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