Definition of Inclusion body myositis
1. Noun. Myositis characterized by weakness of limb muscles (especially the thighs and wrists and fingers); sometimes involves swallowing muscles; onset after 50 and slowly progressive; seen more often in men than in women.
Medical Definition of Inclusion body myositis
1.
Common form of inflamatory myopathy, most common in the elderly, equal sex incidence, sporadic idiopathic disease (very rarely familial), misdiagnosed as steroid-resistant polymyositis symptoms, presents as a painless slowly progressive proximal myopathy, may cause dysphagia, mild to moderate muscle wasting diagnosis, serum creatine kinase levels usually normal or only slightly elevated, EMG may show non-specific myopathic features, diagnosis on muscle biopsy, inclusion bodies seen in rimmed vacuoles in skeletal muscle fibres treatment, steroids and immunosuppression generally ineffective, rare patients reported who have made a response to treatment pathogenesis, unknown, ubiquitin, prion protein, tau protein found in inclusions, abnormal mitchondria seen in some case
(12 Dec 1998)
Lexicographical Neighbors of Inclusion Body Myositis
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