Medical Definition of Indirect fluorescent antibody

1. The detection of antibodies to specific antigenic material in the substrate using fluorescent microscopy. Using fluorescent conjugated antibodies which are specific for a particular isotype of antibody, it is possible to distinguish IgG, IgA and IgM isotypes of specific antibodies using indirect fluorescent antibody. This sensitive technique is highly specific in well-trained hands and recent developments in the establishment of internationally recognised standard materials have led to accurate quantitation of antibody concentrations through endpoint titration (the highest serial dilution of specimen at which specific fluorescence remains) and through measuring visual intensity of fluorescence compared to known reference standard material. (05 Mar 2000)

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Lexicographical Neighbors of Indirect Fluorescent Antibody

indirect Coombs' test
indirect agglutination
indirect antonym
indirect bilirubin
indirect correlation
indirect discourse
indirect diuretic
indirect evidence
indirect expression
indirect fire
indirect fluorescent antibody (current term)
indirect fracture
indirect free kick
indirect haemagglutination test
indirect immunofluorescence
indirect lead
indirect life cycle
indirect lighting
indirect liquefaction
indirect maternal death
indirect nuclear division
indirect object
indirect objects
indirect ophthalmoscope

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