Medical Definition of Interleukin-1

1. A soluble protein (17 kD: 152 amino acids) secreted by monocytes, macrophages or accessory cells involved in the activation of both T-lymphocytes and B lymphocytes and potentiates their response to antigens or mitogens. Its biological effects include the ability to replace macrophage requirements for T-cell activation, as well as affecting a wide range of other cell types. at least two IL-1 genes are active and alpha and beta forms of IL-1 are recognised. It is released early in an immune system response by monocytes and macrophages. It stimulates T-cell proliferation and protein synthesis. Another effect of IL-1 is that it causes fever. See: catabolin, endogenous pyrogen. Acronym: IL-1 (12 Dec 1998)



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Lexicographical Neighbors of Interleukin-1

interleafing
interleaflet
interleafs
interleague
interleave
interleaved
interleaves
interleaving
interleavings
interlegislative
interlend
interlending
interlends
interlent
interleukin
interleukin-1 (current term)
interleukin-10
interleukin-11
interleukin-12
interleukin-13
interleukin-14
interleukin-15
interleukin-16
interleukin-1 converting enzyme
interleukin-2
interleukin-3
interleukin-4
interleukin-5
interleukin-6
interleukin-7

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