Medical Definition of Interleukin-1 converting enzyme

1. Cytoplasmic cysteine protease that is uniquely responsible for cleaving proIL-1_ (31 or 33 kD) into mature IL-1_ (17.5 kD), the active cytokine is then released by a nonstandard mechanism (there is no signal sequence and it does not pass through the Golgi). The enzyme seems to be composed of two nonidentical subunits derived from a single proenzyme. The ICE gene has some homology with the ced 9 gene of C. Elegans, the product of which is involved in mediating cell death by apoptosis. (11 Mar 1998)



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Lexicographical Neighbors of Interleukin-1 Converting Enzyme

interleavings
interlegislative
interlend
interlending
interlends
interlent
interleukin
interleukin-1
interleukin-10
interleukin-11
interleukin-12
interleukin-13
interleukin-14
interleukin-15
interleukin-16
interleukin-1 converting enzyme (current term)
interleukin-2
interleukin-3
interleukin-4
interleukin-5
interleukin-6
interleukin-7
interleukin-8
interleukin-9
interleukine
interleukins
interlevel
interlexeme
interlexemic
interlexical

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