Lexic.us

Definition of Kernicterus

1. Noun. An abnormal accumulation of bile pigment in the brain and other nerve tissue; causes yellow staining and tissue damage.

Definition of Kernicterus

1. Noun. (medicine) Damage to the brain centres of infants caused by increased levels of unconjugated-indirect bilirubin which is free (not bound to albumin). ¹

¹ Source: wiktionary.com

Medical Definition of Kernicterus

1. Disorder due to jaundice in a newborn baby with high blood levels of the pigment bilirubin that is deposited in the brain resulting in damage. The level of bilirubin is monitored in newborns to determine whether treatment is needed to prevent kernicterus. With brain affected, it is also called bilirubin encephalopathy. (12 Dec 1998)

Lexicographical Neighbors of Kernicterus

Literary usage of Kernicterus

Below you will find example usage of this term as found in modern and/or classical literature:

1. Digestive Diseases of the U. S.: Epidemiology and Impact edited by James E. Everhart (1994)
"... unspecified P59 Neonatal jaundice from other and unspecified causes Excludes: due to inborn errors of metabolism (E70-E90) kernicterus (P57. ..."

2. Guide To Clinical Preventive Services by U. S. Preventive Services Task Force (1989)
"... currently occurs at a rate of about 1.5 per 1000 births.5 Its effects on the fetus or newborn include hemolytic anemia, hyperbilirubinemia, kernicterus, ..."

3. Monographic Medicine by Albion Walter Hewlett, Lewellys Franklin Barker, Milton Howard Fussell, Henry Leopold Elsner (1916)
"... it exerts a selective action on the lenticular nuclei, comparable to the selective bile- staining of the lenticular nuclei in "kernicterus" (Rolleston). ..."

4. Recognition & Management of Pesticide Poisoning by Donald P. Morgan (1989)
"In infants, high levels of hemoglobin, methemoglobin, and bilirubin in the plasma may lead to encephalopathy (kernicterus). Some individuals exhibit dermal ..."

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