Medical Definition of Leukotriene a4

1. (2s-(2 alpha,3 beta(1e,3e,5z,8z)))-3-(1,3,5,8-tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-hpete via the stereospecific removal of a proton at c-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., leukotriene b4 and cysteinyl-leukotrienes. Alternatively, leukotriene a4 is converted into leukotriene c4 by glutathione-s-transferase or into 5,6-di-hete by the epoxide-hydrolase. (12 Dec 1998)



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Lexicographical Neighbors of Leukotriene A4

leukotome
leukotomies
leukotomy
leukotoxin
leukotoxins
leukotrichia
leukotrichia annularis
leukotrichous
leukotriene
leukotriene-C4 synthase
leukotriene A4 hydrolase
leukotriene B4 12-hydroxydehydrogenase
leukotriene B4 6-isomerase
leukotriene B4 reductase
leukotriene D4 dipeptidase
leukotriene a4 (current term)
leukotriene b4
leukotriene c4
leukotriene d4
leukotriene e4
leukotrienes
leukæmia
leupeptin
leupeptin acid reductase
leupeptin acid synthetase
leupeptinase
leupeptins
leuprolide
leuprolide acetate
leuprorelin

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