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Medical Definition of Methylthioadenosine
1. Adenosine carrying an -SCH3 group in place of OH at position 5'; the -SCH3 group is transferred to alpha-aminobutyric acid to form l-methionine in some bacteria. Methylthioadenosine is formed from S-adenosyl-l-methionine in the course of spermidine synthesis by loss of the alanine moiety. Synonym: thiomethyladenosine. (05 Mar 2000)