Medical Definition of Negative staining

1. Microscopic technique in which the object stands out against a dark background of stain. For electron microscopy the sample is suspended in a solution of an electron dense stain such as sodium phosphotungstate and then sprayed onto a support grid. The stain dries as structureless solid and fills all crevices in the sample. When examined in the electron microscope the sample appears as a light object against a dark background. Quite fine structural detail can be observed using negative staining and it has been used extensively to study the structure of viruses and other particulate samples. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Negative Staining

negative identification
negative image
negative lens
negative magnetic pole
negative meniscus
negative muon
negative phase
negative pole
negative pressure
negative regulation
negative reinforcer
negative reinforcing stimulus
negative S
negative scotoma
negative stain
negative staining (current term)
negative stimulation
negative stimulus
negative stranded RNA virus
negative strand virus
negative taxis
negative thermotaxis
negative transference
negativing
negativism
negativism
negativisms
negativist
negativistic
negativists

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