Medical Definition of Neurofilament proteins

1. Type III intermediate filament proteins that assemble into neurofilaments, the major cytoskeletal element in nerve axons and dendrites. They consist of three distinct polypeptides, the neurofilament triplet. Types I, II, and IV intermediate filament proteins form other cytoskeletal elements such as keratins and lamins. It appears that the metabolism of neurofilaments is disturbed in alzheimer's disease, as indicated by the presence of neurofilament epitopes in the neurofibrillary tangles, as well as by the severe reduction of the expression of the gene for the light neurofilament subunit of the neurofilament triplet in brains of alzheimer's patients. (can j neurol sci 1990 aug;17(3):302) (12 Dec 1998)



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Lexicographical Neighbors of Neurofilament Proteins

neurofibrils
neurofibroma
neurofibromas
neurofibromata
neurofibromatoses
neurofibromatosis
neurofibromatosis 2
neurofibromin
neurofibromins
neurofibrosarcoma
neurofibrosarcomas
neurofibrosarcomata
neurofilament
neurofilament proteins (current term)
neurofilaments
neurofuran
neurofurans
neuroganglion
neurogastric
neurogenerative
neurogenesis
neurogenetic
neurogeneticist
neurogeneticists
neurogenetics
neurogenic
neurogenic atrophy
neurogenic bladder

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