Medical Definition of Nitroblue tetrazolium
3,3'-(3,3'-dimethoxy-4,4'-biphenylene)bis (2-(p-nitrophenyl)-5-phenyl-2h-tetrazolium. Colourless to yellow dye that is reducible to blue or black formazan crystals by certain cells; formerly used to distinguish between nonbacterial and bacterial diseases, the latter causing neutrophils to reduce the dye; used to confirm diagnosis of chronic granulomatous disease.
Pharmacological action: indicators and reagents.
Chemical name: 2H-Tetrazolium, 3,3'-(3,3'-dimethoxy(1,1'-biphenyl)-4,4'-diyl)bis(2-(4-nitrophenyl)-5-phenyl-, dichloride
(12 Dec 1998)
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