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Medical Definition of No-observed-adverse-effect level

1. The highest dosage administered that does not produce toxic effects. The noael will depend on how closely dosages are spaced (lowest-observed-adverse-effect level and no-observed-effect level) and the number of animals examined. The ultimate objective is usually to determine not the "safe" dosage in laboratory animals but the "safe" dosage for humans. Therefore, the extrapolation most often required of toxicologists is from high-dosage studies in laboratory animals to low doses in humans. (casarett and doull's toxicology: the basic science of poisons, 4th ed) (12 Dec 1998)

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Lexicographical Neighbors of No-observed-adverse-effect Level

No no no(a) no-account no-brainer no-count no-frills(a) no-go no-goal no-good

no-go area no-hit no-hitter no-hit game no-nonsense no-observed-adverse-effect level (current term) no-par-value stock no-parking zone no-par stock no-see-um

no-show no-threshold concept no-win no-win situation no. NOAA Noack's syndrome noah Noah noahs

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