Medical Definition of Oligonucleotide probes

1. Synthetic or natural oligonucleotides used in hybridization studies in order to identify and study specific nucleic acid fragments, e.g., DNA segments near or within a specific gene locus or gene. The probe hybridises with a specific mRNA, if present. Conventional techniques used for testing for the hybridization product include dot blot assays, southern blot assays, and DNA:RNA hybrid-specific antibody tests. Conventional labels for the probe include the radioisotope labels 32p and 125i and the chemical label biotin. (12 Dec 1998)



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Lexicographical Neighbors of Oligonucleotide Probes

oligomerizes
oligomerizing
oligomerous
oligomers
oligomineral
oligomorphic
oligomycin
oligomycin sensitivity conferral protein
oligomycins
oligomyold
oligonephronic
oligonucleosomal
oligonucleosome
oligonucleotidase
oligonucleotide
oligonucleotide probes (current term)
oligonucleotides
oligopepsia
oligopeptidase
oligopeptide
oligopeptide 20
oligopeptide permease
oligopeptides
oligopetalous
oligophagies
oligophagous
oligophagy
oligophenylene
oligophenylenes
oligophosphoglyceroyl-ATP 3'-phosphodiesterase

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