Medical Definition of P-glycoprotein
1.
| A family of integral plasma membrane proteins which, when overexpressed, function as adenosine triphosphate-dependent efflux pumps, causing multidrug resistance.
Mammalian p-glycoproteins are encoded by small mdr gene families. There are several isotypes in multiple species.
See: multidrug transporter.
(22 Sep 2002)
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