Definition of Partition coefficient
1. Noun. (chemistry) The ration of the equilibrium concentrations of a solute in two immiscible solvents ¹
¹ Source: wiktionary.com
Medical Definition of Partition coefficient
Equilibrium constant for the partitioning of a molecule between hydrophobic (oil) and hydrophilic (water) phases.
A measure of the affinity of the molecule for hydrophobic environments and thus, for example: a rough guide to the ease with which a molecule will cross the plasma membrane.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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