Medical Definition of Phosphomannose

1. Mannose derivative formed by phosphorylation in the Golgi complex of certain mannose residues on N glycan chains of lysosomal enzymes. Believed to function as targetting signal that causes entry of these enzymes to the lysosomes. The receptor (215 kD) is enriched in specialised pre lysosomes. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008) An enzyme that catalyses the reversible isomerization of d-mannose-6-phosphate to form d-fructose-6-phosphate, an important step in glycolysis. Chemical name: D-Mannose-6-phosphate ketol isomerase Registry number: EC 5.3.1.8 (12 Dec 1998) Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind. (05 Mar 2000) Involved in biosynthesis of mannitol in celery Registry number: EC 1.1.1.224 Synonym: manp reductase (26 Jun 1999)



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Lexicographical Neighbors of Phosphomannose

phospholipase A2
phospholipase B
phospholipase c
phospholipase d
phospholipases
phospholipases a
phospholipid
phospholipid-hydroperoxide glutathione peroxidase
phospholipid bilayer
phospholipid ethers
phospholipid syndrome
phospholipid transfer protein
phospholipids
phosphomannomutase
phosphomannomutases
phosphomannose (current term)
phosphomannose isomerase-guanosine diphospho-D-mannose pyrophosphorylase
phosphomevalonate kinase
phosphomevalonic acid
phosphomimetic
phosphomolybdic acid
phosphomonoesterase
phosphomonoesterases
phosphomutase
phosphonate
phosphonate esterase
phosphonate monoester hydrolase
phosphonates
phosphonecrosis
phosphoneoepitope

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