|
|
Definition of Phosphoribosyltransferase
1. Noun. (enzyme) Any transferase that involves phosphoribosyl pyrophosphate ¹
¹ Source: wiktionary.com
Medical Definition of Phosphoribosyltransferase
1. One of a group of enzymes (EC sub-subclass 2.4.2, pentosyltransferases) that transfers d-ribose 5-phosphate from 5-phospho-alpha-d-ribosyl pyrophosphate to a purine, pyrimidine, or pyridine acceptor, forming a 5'-nucleotide and inorganic pyrophosphate, or d-ribose from d-ribosyl phosphate to a base, forming a nucleoside, or similar pentose transfers; important in nucleotide biosynthesis. Specific phosphoribosyltransferases are preceded by the name of the acceptor base, e.g., uracil phosphoribosyltransferase (i.e., uracil + PRPP &dblarr; UMP + pyrophosphate). (05 Mar 2000)
Lexicographical Neighbors of Phosphoribosyltransferase
Other Resources:
