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Definition of Piebaldism
1. Noun. (medicine) A rare autosomal dominant disorder of melanocyte development, whose common characteristics include a congenital white forelock, scattered normally-pigmented and hyperpigmented macules, and a triangular depigmented patch on the forehead. ¹
¹ Source: wiktionary.com
Medical Definition of Piebaldism
1. Autosomal dominant, congenital disorder characterised by localised hypomelanosis of the skin and hair. The most familiar feature is a white forelock presenting in 80 to 90 percent of the patients. The underlying defect is possibly related to the differentiation and migration of melanoblasts, as well as to defective development of the neural crest (neurocristopathy). Piebaldism may be closely related to waardenburg's syndrome. (12 Dec 1998)
Lexicographical Neighbors of Piebaldism
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