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Medical Definition of Placental barrier
1. The semipermeable layer of foetal tissue separating the maternal from the foetal blood in the placenta; composed of: 1) endothelium of the foetal vessels in the chorionic villi, 2) stromata of the villi, 3) cytotrophoblast (negligible after the fifth month of gestation), and 4) syncytial trophoblast covering the villi; the placental membrane acts as a selective membrane regulating passage of substances from the maternal to the foetal blood. Synonym: placental barrier. (05 Mar 2000)
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