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Medical Definition of Platelet glycoprotein gpiib-iiia complex
1. Platelet membrane glycoprotein complex important for platelet adhesion and aggregation. The complex is an integrin which recognises the arginine-glycine-aspartic acid (rgd) sequence present on several adhesive proteins. As such, it is a receptor for fibrinogen, von willebrand factor, fibronectin, vitronectin, and thrombospondin. A deficiency of gpiib-iiia results in glanzmann's thrombasthenia. (12 Dec 1998)
Lexicographical Neighbors of Platelet Glycoprotein Gpiib-iiia Complex
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