Medical Definition of Sclerosing adenosis
1. A nodular, benign breast lesion occurring most frequently in relatively young women and consisting of hyperplastic distorted lobules of acinar tissue with increased collagenous stroma; the changes may be difficult to distinguish microscopically from carcinoma. Also, a benign nodular microscopic lesion of the prostate consisting of acimar tissue with increased stroma; the basal cell layer shows characteristic smooth muscle metaplasia. Synonym: adenofibrosis, fibrosing adenomatosis, fibrosing adenosis. (05 Mar 2000)
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