Definition of Spermine

1. Noun. (organic compound) A polyamine, ''N,N'-bis(3-aminopropyl) butane-1,4-diamine'', originally extracted from sperm, that is involved in cellular metabolism ¹

¹ Source: wiktionary.com

Definition of Spermine

1. a chemical compound [n -S]

Medical Definition of Spermine

1. Polybasic amine. Found in human sperm, in ribosomes and in some viruses. Involved in nucleic acid packaging. Synthesis is regulated by ornithine decarboxylase which plays a key role in control of DNA replication. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Literary usage of Spermine

Below you will find example usage of this term as found in modern and/or classical literature:

1. Commercial Organic Analysis: A Treatise on the Properties, Proximate by Alfred Henry Allen, Henry Leffmann, Joseph Merritt Matthews (1896)
"This reaction distinguishes true spermine from commercial piperazine. ... spermine phosphate contains two atoms of nitrogen to one of phosphorus, ..."

2. The Modern Materia Medica: The Source, Chemical and Physical Properties (1911)
"The uses are the same as those of spermine described above. Dose by mouth, 15 to 30 minims; subcu- taneously, half as much, once daily or every second day. ..."

3. Commercial Organic Analysis: A Treatise on the Properties, Proximate by Alfred Henry Allen, Henry Leffmann (1896)
"spermine is a colourless, odourless, crystalline substance, soluble in water and alcohol to form strongly alkaline solutions. spermine phosphate is ..."

4. The Prolongation of Life: Optimistic Studies by Elie Metchnikoff (1908)
"... method—The spermine of Poehl—Dr. Weber's precepts—Increased duration of life in historical times— Hygienic maxims—Decrease in cutaneous cancer MEN of ..."

5. Allen's Commercial Organic Analysis: A Treatise on the Properties, Modes of by Alfred Henry Allen (1913)
"From the spermine phosphate thus prepared the free base is obtained by boiling with ... spermine phosphate is immediately precipitated as crystals on adding ..."

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