Medical Definition of Testicular feminization syndrome
1.
A type of male pseudohermaphroditism characterised by female external genitalia (may be ambiguous if the syndrome is incomplete), incompletely developed vagina often with rudimentary uterus and fallopian tubes, female habitus at puberty but with scanty or absent axillary and pubic hair and amenorrhoea, and testes present within the abdomen or in the inguinal canals or labia majora; epididymis and vas deferens are usually present; androgens and oestrogens are formed, but target tissues are largely unresponsive to androgens; individuals are sex chromatin-negative and have a normal male karyotype; X-linked recessive inheritance; there is a defect in the androgen receptor protein.
(05 Mar 2000)
Lexicographical Neighbors of Testicular Feminization Syndrome
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